Methylene Blue Capsules – USP Grade, 8 mg, 12.5 mg or 20 mg
Methylene Blue Capsules – USP Grade, 8 mg, 12.5 mg or 20 mg
A single-ingredient option for people who want methylene blue on its own.
"I'm a believer in the research supporting combination formulas, which is why NeuroAxis exists. But some people just want a single ingredient. When I find a quality single-ingredient product already on the market, I'd rather carry it than put my own label on it."
Dr. Michael Fitzmaurice, Peripheral Nerve Surgeon
Methylene blue is a compound with more than a century of medical use. Inside the mitochondria, the parts of your cells that produce energy, it can act as an alternative electron carrier, passing electrons along the chain that makes ATP. Most of this research comes from laboratory and animal studies, and human research at supplement doses is still limited.
Why quality matters with methylene blue
Methylene blue is sold in industrial, laboratory and aquarium grades that aren't made for people to take. This product is USP grade, the purity standard set by the United States Pharmacopeia. Every batch is tested by an independent lab for identity, purity, potency, heavy metals, microbes and residual solvents, and a QR code on each bottle links to the Certificate of Analysis for that batch.
Why these strengths
Methylene blue works within a narrow window. In laboratory research, low concentrations support electron flow in the mitochondria, while much higher concentrations do the opposite. The human brain-imaging studies people often cite used single doses of about 4 mg/kg (roughly 280 mg), far above any capsule here. The 8, 12.5 and 20 mg strengths are low-dose formats. If you're new to methylene blue, the 8 mg strength is the most conservative place to start.
What methylene blue may support*
- Normal mitochondrial function
- Cellular energy production
Product details
| Amount per serving | 8 mg, 12.5 mg or 20 mg methylene blue (USP grade), depending on strength |
| Serving size | 1 capsule |
| Bottle sizes | 8 mg: 60 capsules. 12.5 mg and 20 mg: 30 or 60 capsules |
| Other ingredients | Microcrystalline cellulose, hypromellose capsule (vegetarian), magnesium stearate (vegetable source) |
| Testing | Third-party tested every batch; QR code on the bottle links to the batch COA |
| Made in | USA, in a cGMP-registered facility. No artificial colors or synthetic preservatives |
How to use
Take 1 capsule once daily with water or food, or as directed by your healthcare professional. Store in a cool, dry place away from direct sunlight.
Before you start
Methylene blue inhibits an enzyme called MAO-A, so it can interact with medications that raise serotonin. If you take an antidepressant (SSRIs, SNRIs, tricyclics or MAOIs), tramadol, a triptan, or St. John's wort, talk with your provider before using this product, since the combination may need to be avoided or monitored. Also check with your physician first if you have G6PD deficiency, kidney disease or a medical condition, take prescription medication, or are pregnant or nursing.
It's normal for urine to turn blue or green while taking methylene blue. It can also cause falsely low readings on fingertip pulse oximeters.
Interested in nerve support?
Methylene blue isn't part of NeuroAxis, our complete nerve support formula. If you're looking for multi-pathway nerve support, see NeuroAxis here.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Manufactured by Alpinia Labs and sold by Dr. Fitz Nutrition.