Sofon Reviews: Does It Work? A Nerve Surgeon Checks the Label

Nerve Health · Neuropathy Supplement Reviews

Sofon gets two of the three most important numbers right. What it leaves out, and what its marketing says it contains, matters just as much.

If you are reading Sofon reviews because your feet tingle, burn or feel numb, here is the short answer: Sofon is one of the better-dosed labels in its category on alpha-lipoic acid and B12, it leaves out benfotiamine despite marketing that says otherwise, the finished product has never been clinically studied, and its vitamin D dose runs above the adult upper limit.

Most Sofon reviews never get that far. Search the name and you will find page after page that lists the eight ingredients, explains what each one "supports," quotes a satisfied customer and ends with a discount link. Very few turn the bottle around and compare the milligrams with the research.

That is the only fair test for a product like this, especially if you are over 40 and want evidence rather than marketing for nerve discomfort or early neuropathy symptoms. Sofon does not claim a clinical trial of its own. Its argument is that its ingredients are research-backed. So the question is the one I asked of every technique I adopted over more than 20 years as a peripheral nerve surgeon: what was tested, at what dose, and does this match it?

I gave Sofon a short verdict in my label audit of seven neuropathy supplements: two of three, with one surprise. This review goes further. It checks every ingredient against the human trials it borrows credibility from, explains what the research does and does not show, covers Sofon side effects and vitamin D safety, reviews the refund policy behind the complaints, sorts out the look-alike sites, compares Sofon with other nerve supplements, including mine, and shows where a supplement fits (and where it does not) inside a broader multi-pathway plan that also depends on nutrition and lifestyle.

A disclosure before we start. I formulated NeuroAxis, a nerve support supplement sold on this site, and I authored the two published clinical studies on its predecessor formula. That is a conflict of interest, and you should weigh it. It is also why every figure here is sourced, and why NeuroAxis appears later against the same yardstick, including where it falls short.

What Is Sofon Nerve Support Supplement?

Sofon is a dietary supplement marketed for nerve health, circulation and comfort in the hands and feet. It is sold by Enclave BioActives, whose label lists Columbus, Ohio, and it is available on the company's own site, on a separate storefront called trysofon.com, and on Amazon. A bottle holds 60 capsules, the serving is two capsules a day, and one bottle is a 30-day supply.

On the Enclave site, one bottle is $59 plus $4.95 shipping, three bottles are $49 each and six are $39 each, with a further 15% off on subscription. That works out to roughly $1.10 to $2.15 a day. The company advertises a 90-day money-back guarantee, and the fine print behind it matters, so I cover it below.

Sofon Ingredients (Per 2-Capsule Serving)

Label figures from Enclave BioActives label images and the SuppCo label index, October 2026. Bromelain activity calculated from the label's standardization of 2,400 GDU per gram.

Three things stand out before we touch a single study. First, every amount is disclosed. There is no proprietary blend (a group of ingredients listed under one combined weight, hiding how much of each is present). That puts Sofon ahead of Apex Gold and Quiet Nerves, two of its closest search competitors. Second, there is no vitamin B6 at all, which removes one common way nerve supplements cause problems. Third, the label and the marketing disagree. The description at the top of Sofon's own product page says the formula combines alpha-lipoic acid, benfotiamine and B12. The ingredient list on that same page names eight ingredients, and benfotiamine is not one of them. Neither is it on the label image I reviewed.

The Yardstick: What Doses Did the Research Use?

Sofon has no trial of its own, so the comparison has to be ingredient by ingredient. These are the doses used in the human studies that supplements in this category cite. (The full answer key, with every source, is in my seven-label audit.)

Two core ingredients at trial dose, one missing entirely, and a supporting cast with no neuropathy benchmark.

Ingredient by Ingredient: What the Evidence Shows

Alpha-Lipoic Acid at 600 mg: The Strongest Line on the Label

Alpha-lipoic acid (ALA) is an antioxidant that works in both the watery and the fatty compartments of a cell. That matters for nerves, whose membranes and myelin are fat-rich. ALA also helps regenerate the cell's own antioxidants, including glutathione, and it targets the oxidative stress (damage from reactive oxygen molecules) that high blood sugar generates inside nerve tissue.

In the SYDNEY 2 trial, Ziegler and colleagues gave people with diabetic neuropathy 600, 1,200 or 1,800 mg a day for five weeks. 600 mg produced the best balance of benefit and tolerability, and the higher doses mostly added nausea. Sofon's 600 mg matches that dose exactly. The label does not specify the R form, which in practice usually means the racemic 50/50 mix used in the trials, so this is a fair match. More detail is in my alpha-lipoic acid for neuropathy review. Because ALA can lower blood sugar, review any alpha lipoic acid supplement with your doctor or pharmacist first if you take diabetes medication.

Methylcobalamin at 2,000 mcg: The Right Form at a Real Dose

Vitamin B12 does two jobs nerves cannot do without. It drives the methylation cycle that Schwann cells (the cells that build and maintain myelin) depend on, and it prevents abnormal fatty acids from being built into the myelin sheath. When myelin is poorly maintained, signals slow, and on a nerve conduction study that shows up as reduced velocity.

The dose matters because of absorption. The normal pathway through intrinsic factor (a protein made in the stomach) saturates at roughly 1.5 to 2 mcg per meal. Above that, the body absorbs only about 1% of an oral dose by passive diffusion. The trials pooled in the Sawangjit 2020 meta-analysis most often used 1,500 mcg to push meaningful amounts through that route. At 2,000 mcg, Sofon clears that bar, and it uses methylcobalamin rather than cyanocobalamin.

This is the line that most clearly separates Sofon from Nerve Recovery Max, which uses the same form at 2 mcg. If you take metformin or acid-suppressing medication, both of which lower B12 absorption, ask for a B12 level before choosing any product. If B12 alone has not moved your symptoms, read why B12 is not always helping neuropathy.

The Missing Benfotiamine

Benfotiamine is a fat-soluble form of vitamin B1 that reaches tissue thiamine levels plain thiamine cannot. Active thiamine switches on an enzyme called transketolase, which diverts excess sugar breakdown products away from the pathways that damage nerves and into a harmless one. The BENDIP trial (Stracke, 2008) tested 300 and 600 mg a day, with the clearer effect at 600 mg.

Benfotiamine is the third member of the core three for a reason: it works on a different part of the sugar-damage problem than ALA does. Sofon's label leaves it out. That is a formulation choice the company is entitled to make. What a buyer is entitled to is a product description that matches the label, and on the page I reviewed, it did not. If B1 support matters to you, read the Supplement Facts panel on the bottle in your hand, not the description above the buy button. My benfotiamine and methylcobalamin guide explains how the two work together.

Vitamin D at 5,000 IU: Interesting Evidence, Above the Upper Limit

Vitamin D is the most distinctive ingredient on the Sofon label, and the evidence here is more interesting than most people expect. Low vitamin D is common in people with diabetic neuropathy. A 2025 meta-analysis of randomized trials pooled four small studies (320 people with painful diabetic neuropathy) and found a short-term reduction in pain with vitamin D compared with placebo. The authors were careful to say the trials were small, varied in quality and had no long-term follow-up, and that larger trials are needed before routine supplementation can be recommended.

The dose is the issue. The tolerable upper intake level for adults is 4,000 IU a day, and Sofon provides 5,000 IU. That does not make it dangerous for everyone. Plenty of people with a measured deficiency take more under a doctor's direction. But many adults over 40 already take a separate vitamin D or a multivitamin, and the two stack. Ask for a 25-hydroxyvitamin D level before you start, and recheck it after a few months if you stay on it. Vitamin D toxicity raises calcium, and in people with kidney disease or a history of kidney stones that deserves a real conversation with a physician.

Coenzyme Q10 at 100 mg

Peripheral nerves contain some of the longest cells in the body, and every inch of an axon depends on mitochondria. Coenzyme Q10 is part of the mitochondrial energy chain and an antioxidant. In a randomized, placebo-controlled trial, Hernández-Ojeda and colleagues gave 400 mg a day for 12 weeks to people with diabetic polyneuropathy and found improvements in symptom scores and some nerve conduction measures. It was a small study, 49 people. Sofon provides 100 mg, a quarter of that dose.

One detail from that trial is worth holding onto. The researchers also measured nerve growth factor, and it did not change with CoQ10 treatment, even at four times Sofon's dose. Remember that when you get to the marketing claims below.

Green-Lipped Mussel, MSM, Bromelain and Zinc

These four make up Sofon's circulation and inflammation story. The research behind them is mostly in joints, not nerves. Green-lipped mussel extract is studied mainly for osteoarthritis, and the 50 mg here is a concentrated oil extract. MSM is a sulfur compound studied for joint comfort. I am not aware of a human neuropathy trial for either one, so there is no dose to compare against.

Bromelain is an enzyme from pineapple stem, and it is measured by activity, not weight. At 6.25 mg standardized to 2,400 GDU per gram, Sofon provides roughly 15 GDU, a small fraction of the amounts used in bromelain research. I explain why activity units matter in my bromelain review. Zinc at 15 mg is a reasonable nutrition dose, well under the 40 mg upper limit, and it can upset the stomach in some people when taken without food.

What Sofon Gets Right

A fair review says so when a product does something well, and Sofon does several things well. Every amount is disclosed. Alpha-lipoic acid and methylcobalamin are at trial doses, which most competitors in this space miss. There is no high-dose B6, which matters because chronic excess B6 can itself cause a sensory neuropathy (I cover that in vitamin B6 and peripheral neuropathy). The shellfish warning is printed on the storefront. And at roughly $1.10 to $2.15 a day, it costs less than many products in this category, including mine. Sofon's problems are what it leaves out, what its marketing adds, and the vitamin D dose.

Does Sofon Work?

The honest answer is that nobody knows, because nobody has tested it. Sofon is marketed as a daily nerve health formula to support comfort, circulation and nerve nutrition, but there is no published study of the finished product. The question you can answer is whether its doses fall where the individual ingredients showed benefit, and for Sofon the answer is split: yes on ALA and B12, no on benfotiamine and CoQ10, and no benchmark at all for the joint-focused ingredients.

That does not mean nobody who takes it feels better. But a change in symptoms does not tell you what is causing them. Neuropathy symptoms fluctuate on their own. Placebo responses in painful neuropathy trials are substantial, which is exactly why those trials need placebo groups. People who start a supplement often start other things at the same time, such as tighter blood sugar control or more walking. And someone who is low in B12 or vitamin D may genuinely benefit from correcting it. A testimonial cannot separate any of those from the product itself.

The reviews displayed on Sofon's own product page illustrate this well. Alongside enthusiastic reports, a large share of the reviews shown there describe no noticeable change after weeks or months of use. That pattern is what you would expect from a product with no controlled trial behind it: some people improve, some do not, and the reviews cannot tell you why.

It also helps to know what real improvement looks like. In the trials of individual ingredients, symptom changes took roughly 4 to 12 weeks to appear. Structural repair is slower. A regenerating axon grows at about 1 mm a day, a little over an inch a month, so recovery along the length of the leg is measured in many months. I walk through those timelines in how long nerve supplements take to work.

Sofon Side Effects

Most people searching "Sofon side effects" are really asking about the ingredients. For most adults the risk is low, but four points deserve attention.

Shellfish allergy. Green-lipped mussel is a shellfish. Sofon's own storefront says not to use it if you have a shellfish allergy, and that warning should be taken literally.

Stomach upset and heartburn. Alpha-lipoic acid can cause nausea and heartburn, and zinc can upset an empty stomach. A few reviewers on the brand's own page describe heartburn or a burning sensation after taking it, which fits those ingredients. Taking the capsules with food often helps.

Blood sugar. ALA can lower blood glucose. If you take insulin or a sulfonylurea, monitor more closely when you start it.

Vitamin D stacking. At 5,000 IU, adding Sofon to an existing vitamin D supplement can push your total well above the upper limit. Check your level first.

Bromelain can add mildly to the effect of blood thinners, though at roughly 15 GDU that effect is likely small. The most important side effect is not on the label at all. It is the opportunity cost: months spent on any supplement while an untreated B12 deficiency, a rising A1C or a compressed nerve keeps doing damage. If you take prescription medications, have surgery scheduled, or are pregnant, show the bottle to your doctor or pharmacist before starting. That is also the right place to ask about combining Sofon with your prescriptions or other supplements.

Sofon Reviews and Complaints: What People Are Really Asking

Searches for "Sofon reviews and complaints" and "is Sofon nerve supplement legit" usually come down to three questions. Is it a real product? Will I get my money back? Can I trust the reviews? Many people first see Sofon on Amazon, Reddit or social media, which makes it worth verifying the seller and the current offer before buying.

It is a real product with a fully disclosed label from a named company. Nothing I found suggests otherwise. The refund question is where buyers should slow down, because the written policy is narrower than the phrase "90-day money-back guarantee" suggests:

The 90 days are counted from purchase, not from delivery. The company's shipping page estimates 5 to 10 business days for US orders and up to 6 to 8 weeks internationally, so part of the window can pass before the bottle arrives.

On multi-bottle orders, only one opened bottle is refundable. If you open a second bottle of a six-pack, you are refunded for the first bottle plus the unopened ones you send back, not for the second.

A 10% shipping and handling deduction may apply to returned orders, and shipping charges outside the mainland US are not refundable.

None of that is hidden. It is all on the company's refund policy page. But several reviews on Sofon's own product page describe refund frustration, including that deduction and partial refunds, and the policy explains why. Read it before you buy a six-pack, confirm the full cost, shipping and any recurring billing terms before paying, and keep your order confirmation.

The reviews deserve the same care. Sofon's main storefront shows 81 reviews. A second storefront for the same product, trysofon.com, shows a 4.8 out of 5 rating from 26 reviews. Treat ratings on any sales page as marketing, and compare them with the label and the written refund terms. Many of the pages ranking for the name are affiliate articles with purchase links. Before you trust any review, including this one, ask two questions: does the writer earn money if you buy, and do the numbers they quote match the bottle?

Which Sofon Are You Looking At?

This is the part most Sofon reviews miss. Search for the product and you will find several sites using the Sofon name. They do not agree with each other.

The Enclave BioActives product page lists the eight ingredients in the table above, with a 90-day guarantee and pricing from $39 to $59 a bottle (checked October 21, 2026; verify the total at checkout). Its page description mentions benfotiamine, which its own ingredient list does not include.

trysofon.com carries the same pricing and guarantee and routes support to the same company, so it appears to be a second storefront for the same product. It links its refund policy and terms to a third domain, nervebreakthrough.com, and its ingredients page uses headings such as stimulating nerve regeneration. Decide on the current label, the seller and the billing terms, not on testimonials or headings.

thesofon.com calls itself the official Sofon website. It describes a completely different formula: twelve ingredients including turmeric, acetyl-L-carnitine, benfotiamine, magnesium, passionflower, skullcap, feverfew, corydalis and California poppy, and none of the green-lipped mussel, MSM, zinc or bromelain on the actual label. It lists different prices ($49 to $69 a bottle), a 60-day guarantee instead of 90, a ten-minute countdown timer, and an "FDA Approved" badge. Its footer links to well over a hundred other supplement sites. I cannot tell you who operates it or whether it is connected to Enclave BioActives. I can tell you the formula it describes is not the formula on the bottle.

Amazon listings for Sofon describe the formula as restoring nerve growth factor and regenerating nerves, and call it side-effect free. Two notes. The one human neuropathy trial of CoQ10 that measured nerve growth factor found no change, at four times Sofon's dose. And no supplement with ALA, zinc and a shellfish ingredient is free of side effects; it is just generally well tolerated. Claims about regenerating nerves or relieving neuropathy also go beyond the structure/function language supplements are permitted to use.

The FDA does not approve dietary supplements, and it does not approve supplement factories either. Facilities register with the FDA and are expected to follow current Good Manufacturing Practices. A product can come from a registered, GMP-compliant facility without being "FDA approved," and any page that says otherwise is telling you something about its accuracy.

Same name, different sites, different formulas. The panel on your bottle is the one that counts.

How Sofon Compares

Against the other products in my neuropathy supplement reviews, Sofon lands near the top on transparency and in the upper half on core dosing. Here is the core-three comparison, held to the same standard. For the labels at the other end of that scale, see my Nerve Recovery Max review (right forms, wrong doses) and my Quiet Nerves review (no doses disclosed at all).

On the core-three dose check, Sofon comes closer to NeuroAxis than most products in my reviews, and it costs less per day. If the only question were whether the alpha-lipoic acid and B12 lines match the trials, that would be the end of it. It is not the only question, and I would argue it is not the most important one.

The Second Test: How Many Pathways Does the Formula Reach?

Peripheral neuropathy rarely comes from a single mechanism. It develops along several pathways at once, and which ones are involved shapes whether you feel tingling, numbness, weakness or balance trouble. High glucose drives oxidative stress and floods the cell with damaging sugar byproducts. Myelin depends on B vitamins to be built and maintained. Long axons depend on mitochondria to power transport along their length. And the tissue around the nerve, its blood supply and its inflammatory environment, shapes whether the nerve can recover. A single ingredient, however well dosed, works on one of those.

So the second scorecard asks which of those pathways a label actually reaches, and whether the product gives you a plan for the two things that move nerve health more than any capsule: nutrition and lifestyle.

A dose check asks whether each line matches the research. A pathway check asks how much of the problem the formula reaches.

What the Research Says About Combinations

The trend in the research favors combining ingredients that work on different pathways. The clearest example uses exactly the ingredient Sofon leaves out. In an eight-week study by Popa and colleagues (2019), people with diabetic neuropathy who took alpha-lipoic acid together with benfotiamine were far more likely to see their symptoms cut in half (65%) than those taking alpha-lipoic acid alone (28%) or benfotiamine alone (11%). A six-month randomized, placebo-controlled trial by Didangelos and colleagues (2024) tested a ten-ingredient combination including alpha-lipoic acid, B vitamins and palmitoylethanolamide, and found improvements in pain and vibration sense that the placebo group did not show.

Two honest qualifiers belong next to those numbers. The Popa study was small and unblinded, and the benefit faded within 12 weeks of stopping. And most combination trials compare a formula with placebo, not with its own ingredients, so they show that combinations can work without proving the combination beats each part. No finished formula, NeuroAxis included, has been tested head to head against its own ingredients. That is the study I intend to see done. Until then, multi-pathway formulation is the most reasonable reading of how neuropathy develops and where the evidence is trending, not a settled fact.

Here is where NeuroAxis falls short on the dose check, since I put it in the tables. Acetyl-L-carnitine at 600 mg is below the 1,500 to 3,000 mg Sima used, CoQ10 at 150 mg is below the 400 mg trial dose, and benfotiamine sits at the lower of the two BENDIP arms. It is six tablets a day rather than two, and at about $2.00 a day on subscription, with free shipping, it costs more than Sofon. What it does differently is reach all three core nutrients at trial doses and cover every pathway in the table above.

The Supplement Is the Third Pillar, Not the First

The other difference is not in the capsule. I treat any nerve support supplement, including my own, as the third and smallest of three pillars, after nutrition and lifestyle. The reason is the evidence. The human study that actually increased nerve fiber density, a lifestyle intervention trial in people with prediabetic neuropathy (Smith, 2006), used diet and exercise, not pills. That is why every NeuroAxis order includes the 160-page NeuroAxis Protocol, my guide to the nutrition and lifestyle work that comes first. Sofon, like every other product in my reviews, ships as a bottle and nothing more.

That Protocol turns a bottle into a plan:

Pillar 1, Nutrition: how to eat to stabilize blood sugar and reduce the metabolic stress that drives most neuropathy, including the nutrients, such as magnesium, that are better covered by diet than by another capsule.

Pillar 2, Lifestyle: exercise, sleep and daily habits, the interventions with the strongest human evidence for nerve fiber regrowth.

Pillar 3, Targeted nutrients: where NeuroAxis fits, how to take it, and how to track whether it is helping.

So the choice comes down to this. If you want the two core doses Sofon reaches, 600 mg alpha-lipoic acid and 2,000 mcg methylcobalamin, at a lower price, Sofon delivers them. If you want the core three at trial doses, broader pathway coverage and a step-by-step plan for the nutrition and lifestyle work that does the heaviest lifting, that is what NeuroAxis and the NeuroAxis Protocol are built for. And if you are not sure which fits, book a free 10-minute discovery call and I will tell you honestly.

My own clinical studies were on the predecessor formula in carpal tunnel surgery patients, not neuropathy, and I take them apart honestly in my NeuroAxis review.

The Bigger Question: What Is Causing Your Nerve Pain?

No label review answers the most important question, which is why your nerves are misbehaving in the first place. Peripheral neuropathy is damage to nerves outside the brain and spinal cord, and it has well over a hundred causes, including diabetes, prediabetes, B12 and other vitamin deficiencies, thyroid disease, alcohol, chemotherapy, medications, injury and nerve compression. Many of those need cause-specific treatment that no supplement provides. Sofon's marketing leans on sciatica and back pain, and that is worth a specific warning: pain that runs down one leg from the back is usually a compressed nerve root, not a nutritional problem, and it needs an evaluation, not a capsule. Symptoms in one hand or one foot, rather than both, are another reason to get checked, and so is reduced sensation in the feet, which raises the risk of unnoticed pressure sores and burns.

If you are not sure what is driving your symptoms, or whether a supplement makes sense for your situation at all, you can book a free 10-minute nerve health discovery call and talk it through with me directly. Sorting out the likely driver first is how you avoid spending months on the wrong solution.

If you are not sure which tests to ask for, start with which test detects neuropathy, and if your tests came back normal, read why a normal EMG does not rule out nerve damage.

If You Are Taking Sofon Now: A Timeline

Frequently Asked Questions

Does Sofon really work?

Whether Sofon works is uncertain, because no study has tested Sofon itself. Two of its core ingredients are at trial doses: alpha-lipoic acid at 600 mg and methylcobalamin at 2,000 mcg. It contains no benfotiamine or acetyl-L-carnitine, its CoQ10 is a quarter of the trial dose, and its joint-focused ingredients have no neuropathy trials to compare against. Even when someone feels better, a supplement does not address the underlying cause of neuropathy symptoms.

What are the ingredients in Sofon?

Per two-capsule serving: vitamin D 5,000 IU, methylcobalamin 2,000 mcg, zinc 15 mg, alpha-lipoic acid 600 mg, MSM 200 mg, CoQ10 100 mg, green-lipped mussel shell oil extract 50 mg and bromelain 6.25 mg. Every amount is disclosed.

Does Sofon contain benfotiamine?

Not on the label I reviewed. Sofon's product page description mentions benfotiamine, but the ingredient list and Supplement Facts panel do not include it. Check the panel on your own bottle.

What are the side effects of Sofon?

Most people tolerate it well. It contains green-lipped mussel, so it is not suitable for anyone with a shellfish allergy. Alpha-lipoic acid can cause nausea or heartburn and can lower blood sugar, which matters with insulin or sulfonylureas. The 5,000 IU of vitamin D is above the adult upper limit, so check your level and count any other vitamin D you take.

Is Sofon legit or a scam?

Sofon is a real product with a fully disclosed label from a named company, Enclave BioActives. The concerns worth knowing are the missing benfotiamine its marketing mentions, a refund policy narrower than the headline guarantee, and a look-alike site calling itself the official Sofon website that describes a completely different formula.

What is Sofon's refund policy?

The company advertises a 90-day money-back guarantee counted from the purchase date. On multi-bottle orders, only the first opened bottle is refundable along with unopened bottles you return, and a 10% shipping and handling deduction may apply. Read the policy before buying several bottles, and confirm the full price, shipping and any recurring billing terms before paying.

Is Sofon FDA approved?

No dietary supplement is FDA approved. Supplements can make structure/function claims such as supporting healthy nerve function, but not claims to treat, cure or regenerate. A product can come from an FDA-registered, GMP-compliant facility without being FDA approved.

How long does Sofon take to work?

There is no product-specific data. In trials of its individual ingredients at full doses, symptom changes appeared within roughly 4 to 12 weeks. Nerve regeneration proceeds at about 1 mm a day, so structural recovery takes months.

What is a better alternative to Sofon?

Look for a formula with alpha-lipoic acid at 600 mg, methylcobalamin at 1,000 mcg or more and benfotiamine at 300 mg or more, modest B6, and every amount disclosed. Then look past the dose check to how many pathways the formula reaches, since research on combinations is trending toward better results than single ingredients, and pair any supplement with nutrition and lifestyle changes, which have the strongest evidence of all. If you already take prescribed medication for nerve pain, check with your doctor or pharmacist before adding anything.

How much does Sofon cost?

On the Enclave BioActives site in October 2026, one bottle was $59 plus $4.95 shipping, three bottles were $49 each and six were $39 each, with 15% off on subscription. One bottle is a 30-day supply, so the cost runs roughly $1.10 to $2.15 a day. Prices change, so confirm the total at checkout.

Sofon vs NeuroAxis: what is the difference?

Both have 600 mg alpha-lipoic acid and 2,000 mcg methylcobalamin. Sofon has no benfotiamine and costs roughly $1.10 to $2.15 a day. NeuroAxis, which I formulated, adds 300 mg benfotiamine, NAC, 600 mg acetyl-L-carnitine, curcumin and serrapeptase, with more CoQ10 and bromelain, and every order includes the 160-page NeuroAxis Protocol for nutrition, exercise, sleep and progress tracking. It costs about $2.00 a day on subscription.

Label Sources (Reviewed October 2026)

Sofon: Enclave BioActives product page, ingredient list and refund policy, enclavebioactives.com, reviewed October 21, 2026; label images on Amazon (ASIN B0FDQZ6RW6), reviewed October 7, 2026; SuppCo label index entry for Enclave BioActives Sofon; trysofon.com product and ingredients pages; thesofon.com, October 21, 2026. Comparison products: as listed in my neuropathy supplement reviews, October 7, 2026, and my Nerve Recovery Max review, October 16, 2026.

About the Author

Dr. Michael Fitzmaurice, MD is a fellowship-trained peripheral nerve surgeon with a background in nerve physiology, metabolic health, and applied exercise physiology. Through years of surgical practice, during which he performed more than 3,000 peripheral nerve procedures, he has observed the close relationship between metabolic health, cellular energy production, and nervous system function. His work focuses on how physical activity, recovery biology, and nutrition-informed strategies relate to long-term nerve and metabolic health.

He oversees Dr. Fitz Nutrition, an education-first initiative translating evidence-informed research into thoughtfully designed formulations for nerve and metabolic health, and believes that patients who understand the science make better decisions about their care.

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

This content is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. Individual results vary. Always consult a qualified healthcare provider regarding your individual medical situation. Product information reflects publicly available labels and brand websites as of October 2026, and formulations change; check the current label before purchasing. Sofon is a trademark of its owner, who did not sponsor or approve this article. Dr. Fitzmaurice formulated, and has a financial interest in, NeuroAxis, and is the author of both studies on its predecessor formula.